William C. Mobley, MD, PhD

William Mobley, MD, PhD, is a board-certified neurologist who cares for patients with Alzheimer's disease and other memory disorders. He has a special interest in diagnosing and guiding care for patients who have Down syndrome and signs of Alzheimer's disease and other neurological conditions.

Dr. Mobley is also associate dean for neuroscience initiatives at UC San Diego School of Medicine and is director of the Down Syndrome Center for Research and Treatment. He is one of the world's foremost experts on the neurobiology of Down syndrome.

His research focuses on neurotrophic factor signaling, especially in the context of neurodegenerative disorders. These include Alzheimer's disease, Down syndrome and Huntington's disease. His goal is to learn about the causes of dysfunction in neural circuits, which can then lead to developing treatments. The work of his lab has led to novel clinical trials for people with Down syndrome.

Dr. Mobley completed a fellowship and residency in neurology at Johns Hopkins University Hospital in Baltimore, where he was chief resident. He also did a residency in pediatrics at Stanford University Hospital. Dr. Mobley earned his PhD in neuro- and behavioral science and his medical degree from Stanford University School of Medicine. He is board-certified in pediatrics and neurology.

He has received numerous honors and awards, including both the Zenith and Temple Awards for Research in Alzheimer's disease from the Alzheimer's Association, the Cotzias Award from the American Academy of Neurology and the Christian Pueschel Memorial Award for Research in Down Syndrome from the National Down Syndrome Congress.

Dr. Mobley is a fellow of the Royal College of Physicians, the American College of Neuropsychopharmacology and the American Association for the Advancement of Science. In 2004, he was named a member of the Institute of Medicine of the National Academy of Science.

He has published widely, has served on the editorial board of several major professional publications and was editor of the Journal Neurobiology of Disease. In addition, he has served on the scientific advisory committees or boards of a long list of national organizations, ranging from the National Association for Autism Research to the Hillblom Foundation.

In addition, Dr. Mobley served on the National Institute of Neurological Disorders (NINDS) Council from 2003 to 2007 and was named a member of the Committee on Committees of the Society for Neuroscience.

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